How does Tadalis work?

Tadalis contains tadalafil, a phosphodiesterase-5 (PDE5) inhibitor, meaning it temporarily negates the secretion of the PDE5 enzyme. Upon inhibiting the PDE5 enzyme, a chemical called cyclic Guanosine Monophosphate (cGMP) stops degrading. This allows the body to release enough nitric oxide during sexual stimulation. Nitric oxide causes vasodilation, meaning it dilates the blood vessels, including those in the penile organ. This way enough blood is supplied to the penile organ for an erection to occur, but only during sexual stimulation.

How should Tadalis be used?

Tadalis comes as a 20 mg tablet containing tadalafil, which is to be taken orally. You can take the dose with or without food. Talk to your doctor about the dosage that is right for you. The medicine is taken as needed, usually at least 30 to 40 minutes before sexual activity. You should not take the medicine more often than once in a day or two. Your doctor will help you understand how to take this generic tadalafil medicine. Do not take Tadalis along with alcohol, grapefruits, marijuana, or any other illicit substance.

How effective is Tadalis?

Studies have found that tadalafil in both 10 mg and 20 mg showed greater improvement at boosting stronger and long-lasting erections. With Tadalis, most men experience a harder and durable erection with successful penetration and successful intercourse. Particularly, Tadalis 20 mg showed greater improvement in efficacy measures than 10 mg. More than 60% of men reported satisfactory erections with 20 mg tadalafil. As far as safety is concerned, there have been clinically meaningful changes in vital parameters, suggesting the drug is safe and effective for most men with ED.

Which drugs interact adversely with Tadalis?

Tadalis oral pill can interact with other medications you may be taking, which can be harmful or prevent the drug from working. To help avoid such drug interactions, you should let your doctor know about all your medicines, including supplements. Angina drugs (nitrates), high blood pressure or prostate drugs (alpha-blockers), certain HIV drugs like ritonavir and lopinavir/ritonavir, antifungal drugs, certain antibiotics, other ED drugs like sildenafil and vardenafil may interact adversely with Tadalis. Avoid this drug if you take nitrates or alpha-blockers.

Who should not take Tadalis?

Children, women, pregnant women, and breastfeeding mothers should not take this tadalafil medicine. Also, the drug is generally not advised to people with heart disease or cardiovascular issues; kidney dysfunction; liver disease, brain disorders, penile issues like Peyronie’s disease; ophthalmic or eye issues; recent history of stroke or heart attack. Also, people with peptic ulcers or bleeding disorders should not take this ED medication. For more information on the contraindications of Tadalis, check with your doctor.

What are the drug’s side effects?

Tadalis is generally well-tolerated by most men. However, some men may experience mild side effects such as a headache, indigestion or heartburn, nausea, flushing, upset stomach, nasal congestion, or lower back pain. Rarely, some side effects can be serious, such as sudden loss of vision, blurry vision, an erection that lasts longer than 4 hours (priapism), dizziness, chest pain, or breathlessness. If you taking Tadalis for the first time and experience skin rashes or any allergic reactions, it means you are allergic to tadalafil. In such a case, stoking using this medicine.

How long does Tadalis last?

Pharmacologically, tadalafil has a half-life of 17 hours, meaning it can last within the body for 36 hours, which is why you must avoid taking the dose more than once a day or two. It is also important to note that to experience the effects of this ED medication, you must be sexually stimulated. Among all PDE5 inhibitors, tadalafil has a longer duration of action – 36 hours; hence, it is called the weekend pill. Other PDE5 inhibitors like sildenafil and vardenafil have a duration of action of about 4 to 6 hours.

The Bottom Line

Tadalis is a prescription oral medication for men who suffer from erectile dysfunction – a common male sexual issue in which the penile organ fails to get erect due to poor blood supply. It is nothing but a generic version of Cialis. Tadalis usually cost less than Cialis. A 20 mg pill of generic tadalafil costs you $1 to $7. If you think Cialis is way too expensive, you can switch to its generic version Tadalis, which is 85-90% cheaper. You can even buy Tadalis online at a discounted price if you purchase in bulk. Make sure you use this medicine under the supervisor of a doctor.