How does Tadalafil act in the body?

Tadalafil is a PDE-5 inhibitor so it temporarily negates the function of the PDE-5 enzyme in order to prevent further degradation of cyclic Guanosine Monophosphate (cGMP). For erectile dysfunction, the drug works by increasing the blood flow needed to the penile organ for an erection. Upon PDE-5 inhibition and cGMP elevation, the body is able to release enough nitric oxide, a chemical responsible for dilating arteries and increasing blood flow to the penile organ. Remember, as Tadalafil works on your circulatory system, it will not help increase sexual drive or desire.

How to take Tadalafil properly?

Take one whole Tadalafil 20 mg tablet with a glass of water, at least 30 to 60 minutes before planning to indulge in sexual activity. You can take the dose with or without food. Taking this medicine on an empty stomach would yield better effects. The drug may take longer to act if you take it with a heavy meal. Please note that you must take Tadalafil 20 mg when needed but not more than once in 24 hours. Make sure you stay away from alcohol, cannabis, grapefruits, or grapefruit juice while taking this generic ED medication. Do not overdose on this prescription drug.

How long does Tadalafil last?

Tadalafil has an upper hand over other ED medications because it acts quickly and lasts longer. In some men, the drug works in as little as 20 minutes after dosage. The medicine is absorbed into the body more easily, acting much quicker. However, it works much better when taken on an empty stomach. One of the best advantages of Tadalafil is its 36-hour efficacy. It has a long duration of action (36 hours) compared to other ED drugs like sildenafil and vardenafil, which can work up to 4 to 6 hours. A pill taken on Friday evening would give you the efficacy until Sunday morning.

Is tadalafil safe?

In general, Tadalafil is safe and well tolerated. However, it has its own limitation and is not recommended for men who have certain medical conditions or those who take certain medications. For instance, men who have ED but also have cardiovascular disease, liver dysfunction, kidney disease, neurological issues, or a recent history of stroke or heart attack are prohibited from using this medicine. Tadalafil is not safe for men who take chest pain medicines like nitrates, high blood pressure drugs containing alpha-blockers, HIV drugs like protease inhibitors, and riociguat.

Can I take Tadalafil with alcohol?

Doctors often advise not to drink alcohol when you use Tadalafil, as it can aggravate the drug’s side effects such as headaches, dizziness, and hypotension (low blood pressure). Also, alcoholism is one of the risk factors of ED and can affect your ability to get and sustain an erection. However, some studies have found that small amounts of alcohol can be consumed safely when you are under the influence of this drug. A small glass of wine or a pint of beer is fine. You should not binge drink while taking this prescription erectile dysfunction drug.

What if Tadalafil does not work for me?

If the drug fails to work for you for the first time, you should take it one more time after 24 hours. You can try taking the drug several times on different occasions before switching to any other treatment of erectile dysfunction. According to a few guidelines, you should try Tadalafil at least 8 times on separate occasions before deciding whether or not it is working. If you find that Tadalafil 20 mg is still not working, try increasing the dose to 40 mg but only after seeking medical advice. Remember, you should not give up because there is always an option to treat ED.

The Bottom Line

Tadalafil is the active ingredient of Cialis, which is available in a generic version. Cialis and Tadalafil are bioequivalent but the generic version is available at a much lower cost. This generic ED medicine has demonstrated that it is medically identical to Cialis in terms of quality, strength, stability, and efficacy. You can use this generic medicine instead of Cialis if you want to save on your prescriptions. In addition, you can easily buy Tadalafil online at the best price. Make sure you use the drug exactly as advised by your medical provider. Avoid self-medication and overdosing.